Identification of MAN1B1 as a Novel Marker for Bladder Cancer and Its Relationship with Immune Cell Infiltration

Table 2

Univariate and multivariate analysis of OS in BLCA patients.

Characteristics	Total (N)	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
T stage	379
T1 & T2	124	Reference
T3	195	1.997 (1.358–2.939)	<0.001	1.975 (1.019–3.826)	0.044
T4	60	3.095 (1.934–4.954)	<0.001	2.572 (1.154–5.732)	0.021
N stage	369
N0	239	Reference
N1	46	1.858 (1.199–2.879)	0.006	1.634 (0.850–3.142)	0.141
N2 & N3	84	2.581 (1.828–3.646)	<0.001	2.176 (1.206–3.928)	0.010
M stage	213
M0	202	Reference
M1	11	3.136 (1.503–6.544)	0.002	1.028 (0.381–2.777)	0.956
MAN1B1	413
Low	207	Reference
High	206	1.728 (1.286–2.323)	<0.001	1.970 (1.226–3.167)	0.005
Age	413
<=70	233	Reference
>70	180	1.421 (1.063–1.901)	0.018	1.292 (0.804–2.075)	0.289
Gender	413
Female	109	Reference
Male	304	0.849 (0.616–1.169)	0.316