Identification of MAN1B1 as a Novel Marker for Bladder Cancer and Its Relationship with Immune Cell Infiltration

Table 4

Univariate and multivariate analysis of PFI in BLCA patients.

Characteristics	Total (N)	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
T stage	380
T1 & T2	124	Reference
T3	196	1.848 (1.261–2.710)	0.002	2.354 (1.159–4.780)	0.018
T4	60	3.268 (2.043–5.227)	<0.001	2.934 (1.255–6.863)	0.013
N stage	370
N0	239	Reference
N1	46	2.394 (1.548–3.702)	<0.001	1.612 (0.824–3.155)	0.163
N2 & N3	85	3.157 (2.212–4.505)	<0.001	2.340 (1.274–4.300)	0.006
M stage	213
M0	202	Reference
M1	11	6.455 (3.117–13.367)	<0.001	1.770 (0.642–4.882)	0.270
MAN1B1	414
Low	207	Reference
High	207	1.393 (1.038–1.870)	0.027	1.478 (0.893–2.446)	0.128
Age	414
<=70	234	Reference
>70	180	1.066 (0.792–1.435)	0.673
Gender	414
Female	109	Reference
Male	305	0.891 (0.642–1.235)	0.488