Identification of ABCA5 among ATP-Binding Cassette Transporter Family as a New Biomarker for Colorectal Cancer

Table 1

ROC analysis and t-test of ABC transporter family based on GSE44076 dataset.

No.	Gene	Expression (CRC)	Expression (normal)	CRC vs normal		AUC
1	ABCA2^a	2.397	2.438	0.983	↓	0.579	0.0351
2	ABCA3	2.709	2.788	0.972	↓	0.654	0.0346
3	ABCA4	2.425	2.351	1.031	↑	0.653	0.0002
4	ABCA5	4.502	5.747	0.783	↓	0.935	<0.0001
5	ABCA6	2.442	2.795	0.874	↓	0.910	<0.0001
6	ABCA7	3.327	3.261	1.020	↑	0.551	0.1073
7	ABCA8	2.621	3.932	0.667	↓	0.997	<0.0001
8	ABCA9	2.636	3.071	0.858	↓	0.930	<0.0001
9	ABCA10	3.109	3.737	0.832	↓	0.940	<0.0001
10	ABCA12	2.451	2.410	1.017	↑	0.542	0.2877
11	ABCA13	2.223	2.111	1.053	↑	0.510	0.0464
12	ABCB6	Null	Null	Null	—	Null	Null
13	ABCB7	8.012	7.775	1.030	↑	0.680	<0.0001
14	ABCB8	3.08	3.084	0.999	↓	0.520	0.8720
15	ABCB9	2.964	3.008	0.985	↓	0.597	0.0554
16	ABCB10	8.276	8.070	1.026	↑	0.680	<0.0001
17	ABCC6	3.800	4.065	0.935	↓	0.716	<0.0001
18	ABCC8	2.917	2.954	0.987	↓	0.577	0.0490
19	ABCC9	3.061	3.127	0.979	↓	0.502	0.3928
20	ABCC12	2.231	2.197	1.015	↑	0.586	0.0598
21	ABCC13	2.629	3.810	0.690	↓	0.960	<0.0001
22	ABCD1	3.940	3.793	1.039	↑	0.599	0.0090
23	ABCD2	1.985	2.059	0.964	↓	0.673	<0.0001
24	ABCF2	5.292	4.892	1.082	↑	0.806	<0.0001
25	ABCF3	4.837	4.715	1.026	↑	0.692	<0.0001
26	ABCG4	2.152	2.177	0.989	↓	0.567	0.0789
27	ABCG8	2.252	2.278	0.989	↓	0.544	0.3438