Identification of ABCA5 among ATP-Binding Cassette Transporter Family as a New Biomarker for Colorectal Cancer

Table 4

Univariate and multivariate Cox regression analyses of clinical parameters according to the TCGA-COADREAD dataset.

Parameters	Univariate analysis			Multivariate analysis
	HR	95%CI		HR	95%CI
Age
≤60 vs >60	3.036	1.665–5.536	0.000	2.866	1.595–5.150	0.000
Gender
Female vs male	0.708	0.427–1.173	0.180	—	—	—
Clinical stage
I/II vs III/IV	4.811	1.175–19.707	0.029	2.407	1.342–4.317	0.003
T stage
1∼2 vs 3∼4	1.176	0.448–3.090	0.742	—	—	—
N stage
0 vs 1∼3	0.495	0.138–1.774	0.280	—	—	—
M stage
0 vs 1	2.650	1.399–5.021	0.003	2.841	1.540–5.242	0.001
Tumor site
Colon vs rectum	0.779	0.451–1.347	0.372	—	—	—
ABCA5 expression
High vs low	0.474	0.283–0.792	0.004	0.491	0.294–0.820	0.007

HR, hazard ratio; CI, confidence interval.