β-Elemene Restrains PTEN mRNA Degradation to Restrain the Growth of Lung Cancer Cells via METTL3-Mediated N⁶ Methyladenosine Modification

Figure 3

β-Elemene contributed to the decreased METTL3 in lung cancer cells. (a) RT-qPCR detection of m⁶A regulators. (b) The RT-qPCR outcomes of METTL3 expression in A549 together with H1299 cells treated with different concentrations of β-elemene. (c) Western blot was adopted to measure the protein level of METTL3 in A549 together with H1299 cells after exposure to β-elemene. GAPDH acted as an inherent reference. (d) The quantitative outcomes of western blot assay. Experimental data were displayed as mean ± SD, and all assays were repeated thrice.

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