β-Elemene Restrains PTEN mRNA Degradation to Restrain the Growth of Lung Cancer Cells via METTL3-Mediated N⁶ Methyladenosine Modification

Figure 5

β-Elemene executed restrictive impacts on the growth of lung cancer cells in vivo by targeting METTL3. (a) The images of neoplasms from three groups: (1) vector group; (2) vector + β-elemene group; (3) β-elemene + METTL3 group. (b) The weight of xenografts formed by nude mice in indicated groups. (c, d) The volume of tumors formed by nude mice with different administrations. (e) TUNEL staining of lung cancer tissue of different groups. (f-h) The expressions of Bax, Bcl-2, and caspase 3 in the tissues of different groups. Experimental data were represented as mean ± SD, and all assays were repeated thrice.

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