Research Article
Pazopanib in Patients with Osteosarcoma Metastatic to the Lung: Phase 2 Study Results and the Lessons for Tumor Measurement
| Number of patients treated | 12 | Median age (range) years | 32 (18–72) | Median BMI (range) | 30.18 (18.77–48.28) | Gender | | Female | 7 (58%) | Male | 5 (42%) | Race | | African American | 1 (8%) | Asian | 1 (8%) | Caucasian | 7 (58%) | Hispanic | 2 (17%) | Unknown | 1 (8%) | Performance status (ECOG) at cycle 1, day 1a | | 0 | 4 (33%) | 1 | 5 (42%) | 2 | 2 (17%) | Stage at consent | | IVA | 6 (50%) | IVB | 6 (50%) | Grade at consentb | | 1 | 1 (8%) | 2 | 0 (0%) | 3 | 2 (17%) | 4 | 7 (58%) |
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aMissing for one patient at C1D1 (at screening ECOG 0). At screening, ECOG 0/1 was 4/8. bMissing for two patients.
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