Curcumol Targeting PAX8 Inhibits Ovarian Cancer Cell Migration and Invasion and Increases Chemotherapy Sensitivity of Niraparib

Figure 5

Subcutaneous tumor-bearing experiments in nude mice prove that Curcumol inhibits the proliferation and metastasis of ovarian cancer cells. (a). Tumor growth curve of nude mice (Curcumol: 100 mg/kg). (b). Gross picture of nude mouse tumor. (c). Tumor weight of nude mice. (d). Detection of the expression level of PAX8 in two groups of tumor tissues. (e). The expression of E-cadherin in the control and Curcumol treated tissue was detected. (f). Vimentin expression in the control and Curcumol treated tissue was detected. N =6. P <0.05, P <0.01, P <0.001, vs Control group.

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