Research Article
hsa_circ_0001955 Promotes Colorectal Cancer Progression by Regulating miR-583/FGF21 Axis
Figure 7
Overexpression of FGF21 promoted CRC cell proliferation, migration, and invasion and inhibited apoptosis in vitro regulated by miR-583. (a and b) qRT-PCR and western blotting detected FGF21 level in HCT116 cells; (c) CCK-8 detected HCT116 cell proliferation affected by FGF21 and reversed by miR-583; (d and e) Transwell assay detected HCT116 cell migration and invasion affected by FGF21 and reversed by miR-583; (f) flow cytometry detected HCT116 cell apoptosis affected by FGF21 and reversed by miR-583. , , versus NC group.
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