Research Article
Anatomical Resection Improved the Outcome of Intrahepatic Cholangiocarcinoma: A Propensity Score Matching Analysis of a Retrospective Cohort
Table 4
Univariate and multivariate analyses of relative risk of overall survival in the PSM cohort.
| | Variables | Univariate analysis | Multivariate analysis | | HR (95%CI) | | HR (95%CI) | |
| | Group (NAR vs. AR) | 0.661 (0.460–0.949) | 0.025 | 0.655 (0.448–0.958) | 0.029 | | Age (year) (≤60 vs. >60) | 1.089 (0.748–1.585) | 0.657 | | | | Sex (female vs. male) | 0.921 (0.641–1.323) | 0.655 | | | | HBV infection (no vs. yes) | 0.820 (0.527–1.275) | 0.378 | | | | Smoke history (no vs. yes) | 0.913 (0.613–1.359) | 0.652 | | | | Alcohol history (no vs. yes) | 0.959 (0.587–1.567) | 0.868 | | | | Child–Pugh classification (A vs. B) | 0.832 (0.467–1.482) | 0.533 | | | | ALT (U/L) (≤40 vs. >40) | 0.809 (0.517–1.265) | 0.352 | | | | AST (U/L) (≤40 vs. >40) | 1.040 (0.678–1.598) | 0.856 | | | | ALB (g/L) (≤35 vs. >35) | 0.651 (0.409–1.036) | 0.070 | | | | TB (μmol/L) (≤20.5 vs. >20.5) | 1.123 (0.731–1.725) | 0.596 | | | | CA19-9 (U/mL) (≤37 vs. >37) | 1.273 (0.890–1.822) | 0.186 | | | | CEA (ng/mL) (≤20 vs. >20) | 0.849 (0.414–1.740) | 0.654 | | | | AFP (ng/mL) (≤40 vs. >40) | 0.668 (0.211–2.108) | 0.491 | | | | Cirrhosis (no vs. yes) | 1.087 (0.684–1.728) | 0.724 | | | | Laparoscopic approach (no vs. yes) | 0.618 (0.378–1.011) | 0.055 | | | | Robotic approach (no vs. yes) | 0.547 (0.174–1.722) | 0.302 | | | | Portal vein occlusion (no vs. yes) | 1.325 (0.919–1.909) | 0.131 | | | | IVC occlusion (no vs. yes) | 0.999 (0.440–2.272) | 0.999 | | | | Intraoperative transfusion (no vs. yes) | 1.577 (0.867–2.869) | 0.136 | | | | Conversion to open surgery (no vs. yes) | 1.086 (0.568–2.075) | 0.804 | | | | Tumor size (cm) (≤5 vs. >5) | 2.399 (1.666–3.453) | <0.001 | 2.050 (1.393–3.018) | <0.001 | | Tumor number (singular vs. multiple) | 2.573 (1.754–3.775) | <0.001 | 1.962 (1.281–3.006) | 0.002 | | Differentiation (poor vs. well/moderate) | 0.323 (0.213–0.489) | <0.001 | 0.399 (0.261–0.609) | <0.001 | | Lymph node metastasis (no vs. yes) | 1.759 (1.193–2.593) | 0.004 | 0.983 (0.629–1.537) | 0.942 | | Neuron invasion (no vs. yes) | 0.552 (0.175–1.738) | 0.310 | | | | Necrosis in pathology (no vs. yes) | 2.568 (0.941–7.006) | 0.065 | | | | PVTT in pathology (no vs. yes) | 2.198 (0.891–5.418) | 0.087 | | | | Microvascular invasion (no vs. yes) | 1.725 (0.967–3.075) | 0.065 | | |
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