Research Article
Anatomical Resection Improved the Outcome of Intrahepatic Cholangiocarcinoma: A Propensity Score Matching Analysis of a Retrospective Cohort
Table 5
Univariate and multivariate analyses of relative risk of disease-free survival in the PSM cohort.
| | Variables | Univariate analysis | Multivariate analysis | | HR (95%CI) | | HR (95%CI) | |
| | Group (NAR vs. AR) | 0.716 (0.526–0.974) | 0.034 | 0.661 (0.476–0.916) | 0.013 | | Age (year) (≤60 vs. >60) | 0.975 (0.705–1.349) | 0.880 | | | | Sex (female vs. male) | 0.955 (0.701–1.301) | 0.770 | | | | HBV infection (no vs. yes) | 0.804 (0.563–1.148) | 0.230 | | | | Alcohol history (no vs. yes) | 0.811 (0.530–1.242) | 0.335 | | | | Child–Pugh classification (A vs. B) | 0.992 (0.583–1.689) | 0.977 | | | | Smoke history (no vs. yes) | 0.932 (0.664–1.307) | 0.682 | | | | ALT (U/L) (≤40 vs. >40) | 0.799 (0.550–1.160) | 0.238 | | | | AST (U/L) (≤40 vs. >40) | 0.994 (0.692–1.427) | 0.972 | | | | ALB (g/L) (≤35 vs. >35) | 0.677 (0.455–1.007) | 0.054 | | | | TB (μmol/L) (≤20.5 vs. >20.5) | 0.912 (0.620–1.341) | 0.639 | | | | CA19-9 (U/mL) (≤37 vs. >37) | 1.028 (0.756–1.397) | 0.860 | | | | CEA (ng/mL) (≤20 vs. >20) | 1.147 (0.662–1.985) | 0.625 | | | | AFP (ng/mL) (≤40 vs. >40) | 0.961 (0.424–2.175) | 0.924 | | | | Cirrhosis (no vs. yes) | 0.939 (0.623–1.418) | 0.765 | | | | Laparoscopic approach (no vs. yes) | 0.550 (0.363–0.833) | 0.005 | 0.790 (0.505–1.238) | 0.304 | | Robotic approach (no vs. yes) | 0.445 (0.165–1.202) | 0.110 | | | | Portal vein occlusion (no vs. yes) | 1.261 (0.919–1.732) | 0.151 | | | | IVC occlusion (no vs. yes) | 1.327 (0.699–2.521) | 0.387 | | | | Intraoperative transfusion (no vs. yes) | 1.586 (0.945–2.660) | 0.081 | | | | Conversion to open surgery (no vs. yes) | 0.874 (0.474–1.612) | 0.667 | | | | Tumor size (cm) (≤5 vs. >5) | 1.963 (1.439–2.677) | <0.001 | 1.646 (1.170–2.315) | 0.004 | | Tumor number (singular vs. multiple) | 1.771 (1.229–2.553) | 0.002 | 1.185 (0.784–1.185) | 0.422 | | Differentiation (poor vs. well/moderate) | 0.457 (0.331–0.633) | <0.001 | 0.577 (0.410–0.812) | 0.002 | | Lymph node metastasis (no vs. yes) | 1.987 (1.404–2.812) | <0.001 | 1.345 (0.898–2.014) | 0.150 | | Neuron invasion (no vs. yes) | 0.862 (0.404–1.840) | 0.701 | | | | Necrosis in pathology (no vs. yes) | 2.462 (0.905–6.695) | 0.078 | | | | PVTT in pathology (no vs. yes) | 1.457 (0.536–3.959) | 0.461 | | | | Microvascular invasion (no vs. yes) | 1.315 (0.726–2.379) | 0.366 | | |
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