lncRNA KCNQ1OT1 Promotes EMT, Angiogenesis, and Stemness of Pituitary Adenoma by Upregulation of RAB11A

Figure 2

Knockdown KCNQ1OT1 inhibits pituitary adenoma cell stemness and EMT. (a) Validation of the efficiency of knocking down KCNQ1OT1 in GH3 and HP75 cells. (b) Detection of CD44 expression in GH3 and HP75 cells. (c) Detection of Oct4 expression in GH3 and HP75 cells. (d) Detection of CD133 expression in GH3 and HP75 cells. (e) Detection of SOX2 expression in GH3 and HP75 cells. (f) Detection of CD166 expression in GH3 and HP75 cells. (g) Nanog expression detection in GH3 and HP75 cells. (h) Detection of E-cadherin expression in GH3 and HP75 cells. (i) Detection of Vimentin expression in GH3 and HP75 cells. (j) Detection of N-cadherin expression in GH3 and HP75 cells. (k) Detection of Snail1 expression in GH3 and HP75 cells. (l) Slug expression detection in GH3 and HP75 cells. (m) Detection of Twist1 expression in GH3 and HP75 cells. (n) Detection of β-catenin expression in GH3 and HP75 cells. (o) Detection of VE-cadherin expression in GH3 and HP75 cells. (p) Detection of VEGFR1 expression in GH3 and HP75 cells. (q) Detection of VEGFR2 expression in GH3 and HP75 cells. .

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