PLCD1-Induced DNA Damage Inhibits the Tumor Growth via Downregulating CDKs in Chondrosarcoma

Figure 3

PLCD1 overexpression inhibited cell proliferation in vitro. (a) Establishment of OE-PLCD1 HCS-2/8 and SW1353 cell lines. (b, c) Colony formation of the OE-PLCD1 cell line. (d) CCK-8 assay kit revealed a downregulation of cell proliferation by PLCD1 overexpression. (e) Western blotting revealed a downregulation of PCNA expression by PLCD1 overexpression. (f) Flow cytometry analysis revealed cell cycle blocking by PLCD1 overexpression.

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