PLCD1-Induced DNA Damage Inhibits the Tumor Growth via Downregulating CDKs in Chondrosarcoma

Figure 4

Cyclin-dependent kinases (CDKs) expression was downregulated by overexpressing PLCD1 in vitro and in vivo. (a) Western blotting of CDKs and cyclins in KD-PLCD1 cell line in vitro. (b) Western blotting of CDKs and cyclins in OE-PLCD1 cell line in vitro. (c) Antitumor effect of PLCD1 overexpression in vivo. (d) Western blotting of CDKs and cyclins in OE-PLCD1 cell line in vivo.

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