Construction and Validation of a Newly Prognostic Signature for CRISPR-Cas9-Based Cancer Dependency Map Genes in Breast Cancer

Figure 1

Identification of differentially expressed Cancer Dependency Map (CDM) genes in breast cancer and pathway enrichment analyses. (a) Volcano plot of CDM genes in patients with breast cancer from the TCGA database. (b) Heatmap of CDM genes. KEGG pathway enrichment of those downregulated CDM genes (c) and those upregulated ones (d). GO pathway enrichment of those downregulated CDM genes (e) and those upregulated ones (f).

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