Glycoprotein M6A Suppresses Lung Adenocarcinoma Progression via Inhibition of the PI3K/AKT Pathway

Figure 1

Comparison of GPM6A mRNA expression between tumors and corresponding noncancerous tissues. (a) GPM6A mRNA expression in tumors and noncancerous samples in 33 types of cancers in TCGA dataset (red lines: tumor samples; green lines: noncancerous samples). (b) mRNA GPM6A expression in lung adenocarcinoma and normal lung tissues in Hou Lung datasets from the Oncomine database. (c) mRNA GPM6A expression in lung adenocarcinoma and adjacent lung tissues in Su Lung datasets from the Oncomine database. (d) Kaplan–Meier survival analysis for lung adenocarcinoma patients with high and with low GPM6A expression (http://kmplot.com/analysis/) (ID:209469). (e) mRNA GPM6A expression in human lung adenocarcinoma cell lines (A549, H1299) and normal pulmonary epithelial cells (BEAS-2B). Data shown are the mean ± standard deviation (SD) for three independent experiments. ().

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