Identification of Downregulated Exosome-Associated Gene ENPP1 as a Novel Lipid Metabolism and Immune-Associated Biomarker for Hepatocellular Carcinoma

Figure 7

Relationship between ENPP1 expression and tumor-infiltrating immune cells in LIHC. (a) The Xiantao Xueshu indicated the correlation between ENPP1 level and the infiltrating immune cells, (b) the histogram showed the downregulated Th1 cells, DC, and NK CD56bright in ENPP1-highly expressed group, and (c) the histogram shows the negative relationship between ENPP1 and infiltration of Th1 cells, DC, and NK CD56bright. (d) Heat map and (e) scatter plot showed the negative correlation between ENPP9 and three immune checkpoints, PDCD1, HAVCR2, and CTLA4.

(a)

(b)

(c)

(d)

(e)