Research Article

Efficacy of DC-CIK Immunotherapy Combined with Chemotherapy on Locally Advanced Gastric Cancer

Table 3

Comparison of immunological indicators of patients in the two studied groups.

DC-CIK group n = 53Control group n = 53 value

CD3+ T cell (%)
 Pretreatment55.17 ± 3.7356.39 ± 4.400.127
 Post-treatment60.61 ± 3.6353.62 ± 3.840.001

CD4+ T cell (%)
 Pretreatment33.13 ± 4.0932.75 ± 4.030.631
 Post-treatment36.51 ± 4.4729.88 ± 4.080.001

CD8+ T cell (%)
 Pretreatment27.17 ± 5.1428.21 ± 5.160.301
 Post-treatment26.34 ± 5.1928.65 ± 5.140.023

CD4+/CD8+ ratio
 Pretreatment1.43 ± 0.121.44 ± 0.130.682
 Post-treatment1.56 ± 0.141.17 ± 0.130.001

NK cell (%)
 Pretreatment16.52 ± 3.9817.39 ± 4.090.270
 Post-treatment20.19 ± 4.2215.59 ± 4.490.001

Notes: DC-CIK: dendritic cell-cytokine-induced killer.