Licoflavone A Suppresses Gastric Cancer Growth and Metastasis by Blocking the VEGFR-2 Signaling Pathway

Figure 5

LA suppressed the migration and invasion capacities of VEGF-stimulated MKN-45 cells. VEGF-stimulated MKN-45 cells were treated with LA for 72 h. (a) Transwell assays without or with Matrigel were carried out to evaluate the migration and invasion capacity. (b) The numbers of migrated and invaded cells were quantified. Scar  μm. The data are presented as (). vs. and vs. . ^# vs. and ^## vs. . (c) Western blot analysis of EMT-regulated proteins MMP2, MMP9, E-cadherin, and N-cadherin.

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