Research Article

Licoflavone A Suppresses Gastric Cancer Growth and Metastasis by Blocking the VEGFR-2 Signaling Pathway

Figure 8

The schematic representation of the proposed model. LA inhibits activation of VEGFR2, blocking downstream PI3K/AKT and MEK/ERK signaling pathways, which represses GC cell proliferation and metastasis, and induces cycle arrest as well as apoptosis.