Prp19 Facilitated p21-Dependent Senescence of Hepatocellular Carcinoma Cells

Figure 1

Prp19 facilitates the senescence of L02 cells. (a) Cell cycle distribution of L02 cells transfected with myc-Prp19. (b) The effects of Prp19 on senescence of L02 cells were assessed using SA-β-galactosidase staining with or without incubation of 10 μM cisplatin for 24 h. (c) The effects of Prp19 on H-ras-induced senescence of L02 cells were assessed using SA-β-galactosidase. Null vector, NV. The data are shown as the mean ± SEM. Similar results were observed in three independent experiments. , , and . Black scale bar: 100 μm.

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