Research Article
Oleanolic Acid (OA) Targeting UNC5B Inhibits Proliferation and EMT of Ovarian Cancer Cell and Increases Chemotherapy Sensitivity of Niraparib
Figure 3
Knockdown of UNC5B gene inhibits the growth of ovarian cancer tumors. (a) Representative pictures of tumors in the control group and UNC5B knockdown group. Nā=ā6. (b) Detection of the tumor volume of SKOV3 cells transfected with sh-UNC5B. (c) Detection of the tumor weight of SKOV3 cells transfected with sh-UNC5B and sh-NC. (d) Detection of the expression of UNC5B in the tumor tissue after sh-UNC5B transfected SKOV3 cells are tumor-bearing. (e) Detection of the expression of E-cadherin in the tumor tissue after sh-UNC5B transfected SKOV3 cells are tumor-bearing. (f) Detection the expression of vimentin in tumor tissues after sh-UNC5B transfected SKOV3 cells are tumor-bearing. .
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