Correlation between Ultrasonographic Appearance of Papillary Thyroid Microcarcinoma and BRAF V600E Mutation

Table 3

Univariate and multivariate Cox regression of ultrasonographic appearances for PTMC.

	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Location	0.617 (0.315~1.208)	0.159	—	—
Gender	1.728 (0.851~3.507)	0.130	—	—
Age (years)	0.903 (0.499~1.635)	0.737	—	—
Border echo	4.333 (2.313~8.118)	<0.001	6.812 (2.897~16.016)	<0.001
Internal echo	2.697 (1.205~6.034)	0.016	7.977 (3.211~19.817)	<0.001
Morphology	4.500 (2.381~8.503)	<0.001	6.154 (2.687~14.095)	<0.001
Microcalcification	2.629 (1.312~5.269)	0.006	6.768 (2.835~16.159)	<0.001
Aspect ratio	3.392 (1.417~8.121)	0.006	2.054 (0.862~4.894)	0.104
Attenuation	0.412 (0.199~0.853)	0.017	0.208 (0.076~0.572)	0.002
Cystic change	4.929 (2.072~11.721)	<0.001	7.313 (2.521~21.211)	<0.001
Blood flow	1.091 (0.591~2.014)	0.781	—	—
Elasticity modulus value	2.638 (1.438~4.838)	0.002	3.074 (1.369~6.901)	0.006

: statistically different; : not statistically different.