Correlation between Ultrasonographic Appearance of Papillary Thyroid Microcarcinoma and BRAF V600E Mutation

Table 5

Univariate and multivariate Cox regression of ultrasonographic appearances for BRAF V600E mutation.

	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Location	0.985 (0.422~2.297)	0.972	—	—
Gender	1.343 (0.483~3.733)	0.572	—	—
Age (years)	1.693 (0.762~3.761)	0.196	—	—
Border echo	7.667 (2.853~20.602)	<0.001	17.889 (3.674~87.093)	<0.001
Internal echo	0.439 (0.109~1.764)	0.246	—	—
Morphology	0.167 (0.052~0.532)	0.002	0.070 (0.012~0.414)	0.003
Microcalcification	0.646 (0.218~1.910)	0.430	—	—
Aspect ratio	7.308 (2.666~20.035)	<0.001	23.476 (4.555~121.004)	<0.001
Attenuation	6.668 (1.299~34.241)	0.023	2.079 (0.345~12.541)	0.425
Cystic change	0.163 (0.019~1.377)	0.096	—	—
Blood flow	0.623 (0.275~1.413)	0.258	—	—
Elasticity modulus value	2.513 (1.105~5.712)	0.028	1.995 (0.228~17.475)	0.533

: statistically different; : not statistically different.