Effects of Long Noncoding RNA HOXA-AS2 on the Proliferation and Migration of Gallbladder Cancer Cells

Figure 6

HOXA-AS2 affects the proliferation and invasion of gallbladder cancer cells through the regulation of YAP1 on the Hippo pathway. (a) Western blot detection of YAP and TAZ phosphorylation activation in Hippo signaling pathway after HOXA-AS2 silencing. (b) Luciferase activity detection of TEAD transcription factor activation after HOXA-AS2 downregulation (c). Clonal formation assay to detect Hippo pathway agonist-stimulation cell proliferation ability. (d) Transwell assay to detect cell invasion ability after Hippo pathway agonist stimulation.

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