Research Article
Huaier Inhibits Gastric Cancer Growth and Hepatic Metastasis by Reducing Syntenin Expression and STAT3 Phosphorylation
Table 2
Correlations between the syntenin expression level and the clinicopathological features of GC patients.
| Variables | Syntenin expression | Total | χ2 | value | High | Low |
| Age (years) | ≤65 | 44 | 43 | 87 | 4.170 | 0.041 | >65 | 33 | 15 | 48 | | Sex | Female | 21 | 15 | 36 | 0.034 | 0.854 | Male | 56 | 43 | 99 | | Borrmann type | I + II | 41 | 37 | 78 | 1.508 | 0.219 | III + IV | 36 | 21 | 57 | | Lauren type | Intestinal GC | 41 | 30 | 71 | 2.319 | 0.314 | Diffuse GC | 27 | 16 | 43 | | Mixed GC | 9 | 12 | 21 | | Grade of differentiation | Well + moderate | 42 | 31 | 73 | 0.016 | 0.899 | Poor + not | 35 | 27 | 62 | | T stage | T1 | 0 | 2 | 2 | 3.419 | 0.064 | T2 + T3 + T4 | 77 | 56 | 133 | | N stage | N0 | 8 | 3 | 11 | 0.607 | 0.436 | N1 + N2 + N3 | 69 | 55 | 124 | | M stage | M0 | 66 | 56 | 122 | 4.465 | 0.035 | M1 | 11 | 2 | 13 | | TNM stage | I + II | 5 | 12 | 17 | 6.057 | 0.014 | III + IV | 72 | 46 | 118 | | CEA (ng/ml) | ≤5 | 56 | 43 | 99 | 0.034 | 0.854 | >5 | 21 | 15 | 36 | | HER2 | Negative | 65 | 51 | 116 | 0.338 | 0.561 | Positive | 12 | 7 | 19 | | PD-L1 | Negative | 42 | 40 | 82 | 2.885 | 0.089 | Positive | 35 | 18 | 53 | |
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Statistically significant ( ). |