Paeoniflorin Regulates NEDD4L/STAT3 Pathway to Induce Ferroptosis in Human Glioma Cells

Figure 2

NEDD4L was lowly expressed in glioma and is associated with the prognosis of patients. (a) Expression of NEDD4L in TCGA glioma and normal tissue samples. (b) GSEA analysis of NEDD4L high and low TCGA samples showed negative correlation between NEDD4L expression and STAT3 signaling pathway. (c) IHC staining of NEDD4L and STAT3 in glioma tissue chip (left) and Kaplan-meier survival analysis of NEDD4L high and low glioma patients (right).