Kupffer Phase Radiomics Signature in Sonazoid-Enhanced Ultrasound is an Independent and Effective Predictor of the Pathologic Grade of Hepatocellular Carcinoma

Table 4

Univariate analysis and multivariate analysis m/p-HCC versus w-HCC.

Variables	Univariate				Multivariate
	log (OR)	(0.025	0.975)		log (OR)	(0.025	0.975)
AFP	0.000	0.000	0.000	1
TBil	0.009	−0.005	0.023	0.224
DBil	0.009	−0.006	0.023	0.226
AST	−0.001	0.007	0.004	0.641
ALT	−0.003	−0.010	0.003	0.327
CA125	0.000	−0.006	0.005	0.86
CA199	0.016	0.004	0.029	0.007	0.011	−0.009	0.031	0.269
CA153	0.009	−0.045	0.063	0.755
grayRS	−3.165	−8.381	2.052	0.234
APRS	−1.813	−4.792	1.166	0.233
KPRS	14.454	7.154	21.753	<0.001	12.520	5.333	19.707	0.017
const.					−11.093	−17.036	−5.151	<0.001

AFP, alpha-fetoprotein; TBil, total bilirubin; DBil, direct bilirubin; AST, aspartate transaminase; ALT, alanine transaminase; CA, carbohydrate antigen; grayRS, gray scale radiomic score; APRS, arterial phase radiomic score; KPRS, Kupffer phase radiomic score; const., constant.