Posttranslational Modifications of Rev-Erbα Protein and Abnormal Inflammatory Response in Gastric Cancer

Figure 3

Rev-erbα protein phosphorylation is unchanged in gastric cancer cells line BGC-823 and in MNU/H. pylori-induced mouse gastric tumor tissues. (a, c) Levels of Rev-erbα protein phosphorylation were determined in normal human gastric mucosal epithelial cells (GES-1) and human gastric cancer cell lines (BGC-823) in the logarithmic growth phase by Western blot. (b, d) Rev-erbα protein phosphorylation at Ser55/59 and Thr275 was detected in normal control mice and MNU/H. pylori-induced mouse gastric cancer tissues. Calnexin was used as a housekeeping control. Mean ± SEM, N  = 4–6.

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