Marine-Derived Stichloroside C2 Inhibits Epithelial–Mesenchymal Transition and Induces Apoptosis through the Mitogen-Activated Protein Kinase Signalling Pathway in Triple-Negative Breast Cancer Cells

<div>Effect of stichloroside C2 (STC2) on MAPK pathway-related protein expression in triple-negative breast cancer (TNBC) cells. (a) MDA-MB-231 and 4 T1 cells were treated with different concentrations of STC2 (0.25, 0.5, and 1 <i>μ</i>M) for 6 h. Western blotting was used to detect the protein expression and phosphorylation levels of p38, JNK, ERK1/2, and Akt, the main subfamilies of the MAPK signalling pathway family. 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Journal of Oncology

fig6

Figure 6

Figure 6: Marine-Derived Stichloroside C2 Inhibits Epithelial–Mesenchymal Transition and Induces Apoptosis through the Mitogen-Activated Protein Kinase Signalling Pathway in Triple-Negative Breast Cancer Cells 

Figure 6 | Marine-Derived Stichloroside C2 Inhibits Epithelial–Mesenchymal Transition and Induces Apoptosis through the Mitogen-Activated Protein Kinase Signalling Pathway in Triple-Negative Breast Cancer Cells 