Autophagy Induced by Muscarinic Acetylcholine Receptor 1 Mediates Migration and Invasion Targeting Atg5 via AMPK/mTOR Pathway in Prostate Cancer

Figure 6

CHRM1 induces autophagy via AMPK/mTOR pathway in prostate cancer cells. (a-b) Determination and quantification of pathway-related protein expression levels in PC-3 sh-NC and sh-CHRM1 cells by western blotting. . (c-d) Determination and quantification of changes of pathway-related protein in PC‐3 sh-NC and sh-Atg5 cells by western blotting. ; . (e) Graphical schematic of the autophagy induced by CHRM1, which mediates migration and invasion targeting Atg5 via AMPK/mTOR pathway in prostate cancer.

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