Integrin α6 Indicates a Poor Prognosis of Craniopharyngioma through Bioinformatic Analysis and Experimental Validation

Table 1

Gene ontology analysis for aberrant differentially expressed genes in craniopharyngioma.

Category	Term	Count	%	value
Low expression
GOTERM_BP_DIRECT	GO:1902018 ~ negative regulation of cilium assembly	2	3.64	0.01697
GOTERM_BP_DIRECT	GO:0072577 ~ endothelial cell apoptotic process	2	3.64	0.01697
GOTERM_BP_DIRECT	GO:0006355 ~ regulation of transcription, DNA-templated	9	16.36	0.02695
GOTERM_BP_DIRECT	GO:0070588 ~ calcium ion transmembrane transport	3	5.45	0.034121
GOTERM_BP_DIRECT	GO:0042462 ~ eye photoreceptor cell development	2	3.64	0.043071
High expression
GOTERM_CC_DIRECT	GO:0005925 ~ focal adhesion	30	9.35
GOTERM_CC_DIRECT	GO:0070062 ~ extracellular exosome	90	28.12
GOTERM_CC_DIRECT	GO:0009986 ~ cell surface	28	8.75
GOTERM_CC_DIRECT	GO:0005615 ~ extracellular space	46	14.35
GOTERM_CC_DIRECT	GO:0031012 ~ extracellular matrix	18	5.63
GOTERM_BP_DIRECT	GO:0007155 ~ cell adhesion	28	8.75
GOTERM_BP_DIRECT	GO:0030198 ~ extracellular matrix organization	17	5.31
GOTERM_BP_DIRECT	GO:0016337 ~ single organismal cell-cell adhesion	9	2.81
GOTERM_BP_DIRECT	GO:0071404 ~ cellular response to low-density lipoprotein particle stimulus	4	1.25
GOTERM_BP_DIRECT	GO:0042060 ~ wound healing	8	2.50
GOTERM_MF_DIRECT	GO:0050839 ~ cell adhesion molecule binding	8	2.50
GOTERM_MF_DIRECT	GO:0001948 ~ glycoprotein binding	8	2.50
GOTERM_MF_DIRECT	GO:0004871 ~ signal transducer activity	13	4.06
GOTERM_MF_DIRECT	GO:0098641 ~ cadherin binding involved in cell-cell adhesion	15	4.69
GOTERM_MF_DIRECT	GO:0005515 ~ protein binding	166	51.88