Integrin α6 Indicates a Poor Prognosis of Craniopharyngioma through Bioinformatic Analysis and Experimental Validation

Table 2

Results of KEGG enrichment for the differentially expressed genes.

Category	Term	Count	%	value	Genes
Low expression
KEGG_PATHWAY	hsa04972: pancreatic secretion	3	5.454545	0.009187	CEL, ATP2B3, GNAS
KEGG_PATHWAY	hsa04261: adrenergic signaling in cardiomyocytes	3	5.454545	0.019518	ATP2B3, CACNB2, GNAS
High expression
KEGG_PATHWAY	hsa05200: pathways in cancer	18	5.625		PTGER3, PTGS2, ERBB2, CDH1, GLI3, MMP2, CTNNB1, JUP, MAPK1, CBLC, ITGA6, RAC2, JUN, SLC2A1, RAC1, LAMC1, HHIP, FGF1
KEGG_PATHWAY	hsa04510: focal adhesion	14	4.375		ERBB2, TNC, ITGB5, FLNA, MYL9, CTNNB1, MAPK1, ITGA6, RAC2, JUN, RAC1, LAMC1, SPP1, PARVA
KEGG_PATHWAY	hsa05205: proteoglycans in cancer	13	4.0625		LUM, ERBB2, ITGB5, TLR4, MMP2, FLNA, CTNNB1, CBLC, MAPK1, SDC1, CD44, RAC1, MSN
KEGG_PATHWAY	hsa04151: PI3K-Akt signaling pathway	12	3.75	0.022876	MAPK1, SGK1, YWHAZ, ITGA6, TNC, RAC1, YWHAB, ITGB5, TLR4, LAMC1, FGF1, SPP1
KEGG_PATHWAY	hsa04810: regulation of actin cytoskeleton	11	3.4375	0.001989	MAPK1, ENAH, ITGA6, RAC2, CHRM3, RAC1, ITGB5, ITGB2, MSN, FGF1, MYL9
KEGG_PATHWAY	hsa05412: arrhythmogenic right ventricular cardiomyopathy (ARVC)	8	2.5	9.23E-05	JUP, ITGA6, DSG2, ITGB5, GJA1, DSP, CACNA2D3, CTNNB1