TRPV1 Is a Potential Tumor Suppressor for Its Negative Association with Tumor Proliferation and Positive Association with Antitumor Immune Responses in Pan-Cancer

Figure 4

Correlations of TRPV1 expression with tumor immunosuppressive signature scores and ratios of CD8+ T cell/PD-L1. The significant negative correlation between TRPV1 expression levels and tumor immunosuppressive signatures’ scores (a). TRPV1 expression levels correlate positively with the ratios of CD8+ T cell/PD-L1 (b). Pearson’s or Spearman’s correlation test value < 0.05 indicates a significant correlation; the correlation coefficients ( or ) are shown. All analyses were performed in 10 cancer types, while only the cancer types in which the results were significant () are shown in the figure.

(a)

(b)