Research Progress and Prospects of Autophagy in the Mechanism of Multidrug Resistance in Tumors

Figure 5

Three main types of autophagy. Macroautophagy depends on the formation of cytosolic phagophores to encapsulate and transport contents to the lysosome. Microautophagy absorbs the contents directly through the invagination of the lysosomal membrane. Chaperone-mediated autophagy transports the proteins directly across the membrane of the lysosome for digestion.