EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress

Figure 2

Effects of EGCG on apoptosis of irinotecan pretreated RKO and HCT116 cells. Annexin V-FITC&PI double staining was applied to determine the apoptosis rate of RKO (a) and HCT116 (b) cells and FlowJo software was used to fit the data (c, d). Apoptosis-related proteins with EGCG dose (e) and treatment time (f) were carried out by western blot. , , , and (vs control group); , , and (vs IRI 0.5 µM group).

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