DNA Repair Protein HELQ and XAB2 as Chemoresponse and Prognosis Biomarkers in Ascites Tumor Cells of High-Grade Serous Ovarian Cancer

Figure 1

HELQ and XAB2 were associated with poor survival in patients with ovarian cancer. (a–c) Kaplan-Meier curves of OS and PFS according to the expressions of HELQ, XAB2, and RPA2 in TCGA tuboovarian high-grade serous carcinoma. (d–f) Kaplan-Meier survival curves for OS and PFS of patients with HGSC from the study cohort according to expressions of HELQ, XAB2, and RPA2 in ascites tumor cells. (g) Kaplan-Meier survival curves for OS and PFS of patients with HGSC from the study cohort according to HELQ-XAB2 stratification in ascites tumor cells. HELQ: helicase, POLQ like; RPA2: replication protein A2; XAB2: XPA binding protein 2; TCGA: The Cancer Genome Atlas; OS: overall survival; PFS: progression-free survival; HGSC: high-grade serous ovarian cancer.

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