DNA Repair Protein HELQ and XAB2 as Chemoresponse and Prognosis Biomarkers in Ascites Tumor Cells of High-Grade Serous Ovarian Cancer

Figure 2

HELQ and XAB2 expressions in ascites tumor cells associated with platinum-resistant phenotype. (a) Representative immunohistochemistry images of HELQ and XAB2 in patients with platinum-resistant and platinum-sensitive phenotypes. (b) Frequency of platinum-resistant patients from the study cohort was compared according to HELQ and XAB2 expressions. (c) Receiver operator characteristic curves with AUC according to relative expressions of HELQ and XAB2 in ascites tumor cells of patients with HGSC. AUC: area under the curve.

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