DNA Repair Protein HELQ and XAB2 as Chemoresponse and Prognosis Biomarkers in Ascites Tumor Cells of High-Grade Serous Ovarian Cancer

Figure 4

HELQ and XAB2 expressions in tumor tissues were correlated with that in ascites tumor cells. (a) Representative immunohistochemistry images of HELQ and XAB2 in tumor tissues of HGSC patients with platinum-resistant and platinum-sensitive phenotypes. (b) Frequency of platinum-resistant patients from the study cohort was compared according to HELQ and XAB2 expressions in tumor tissues. (c). Expressions of HELQ and XAB2 in ascites tumor cells were used to analyze the correlation with that in matched tumor tissues.

(a)

(b)

(c)