DNA Repair Protein HELQ and XAB2 as Chemoresponse and Prognosis Biomarkers in Ascites Tumor Cells of High-Grade Serous Ovarian Cancer

Table 1

Clinicopathologic characteristics of 60 HGSC patients in Xiangya hospital.

Clinicopathologic parameters	Frequency (%)	Expression level in ascites tumor cells
		HELQ			XAB2
		High	Low		High	Low
Age (year)				0.153			>0.99
≤60	48 (80)	10	38		12	36
>60	12 (20)	5	7		3	9
FIGO stage				—			—
I-II	3 (5)	0	3		0	3
III-IV	57 (95)	15	42		15	42
Residual disease				0.637			0.428
R0	14 (23)	2	12		2	12
R1	29 (48)	8	21		7	22
>R1	17 (28)	5	12		6	11
Ascitic fluid (ml)				0.313			0.313
≤500	15 (25)	2	13		2	13
>500	45 (75)	13	32		13	32
Chemotherapy response				<0.001			0.006
Sensitive	48 (80)	6	42		8	40
Resistant	12 (20)	9	3		7	5

value was calculated by chi-square test. HGSC: high-grade serous ovarian cancer; FIGO: International Federation of Gynecology and Obstetrics. Statistically significant ().