Research Article
DNA Repair Protein HELQ and XAB2 as Chemoresponse and Prognosis Biomarkers in Ascites Tumor Cells of High-Grade Serous Ovarian Cancer
Table 2
Diagnostic performances of HELQ and XAB2 expression levels in ovarian cancer with platinum resistance.
| | Triage | Diagnostic accuracy (95% CI) | | Sensitivity | Specificity | PPV | NPV |
| | High expression of HELQ | 75% (43-93) | 87.5% (74-95) | 60% (33-83) | 93.3% (81-98) | | High expression of XAB2 | 58.3% (29-84) | 83.3% (69-92) | 46.7% (22-73) | 88.9% (75-96) | | High expression of both HELQ and XAB2 | 50% (22-78) | 100% (91-100) | 100% (52-100) | 88.9% (77-95) |
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PPV: positive predictive value; NPV: negative predictive value.
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