Research Article
Tumor Characteristics Associated with Lymph Node Metastasis and Prognosis in Patients with ERBB2-Positive Gastric Cancer
Table 2
Univariate analyses of risk factors for lymph node metastasis.
| Variable | Nodal-positive group | Nodal-negative group | χ2 | value |
| Gender | | | 0.301 | 0.583 | Male | 67 | 31 | | | Female | 15 | 9 |
| Age (years) | | | 0.084 | 0.772 | ≤60 | 14 | 6 | | | >60 | 68 | 34 |
| Tumor size | | | 7.342 | 0.007 | ≤4 cm | 36 | 28 | | | >4 cm | 46 | 12 |
| Depth of invasion | | | 22.987 | <0.001 | PT1 | 2 | 13 | | | PT2 | 6 | 3 | PT3 | 41 | 16 | PT4a/PT4b | 33 | 8 |
| Histologic classification | | | 0.606 | 0.436 | Moderately differentiated | 41 | 17 | | | Moderately poorly differentiated | 32 | 22 | Poorly differentiated | 9 | 1 |
| Histology | | | 2.173 | 0.140 | Conventional AD | 65 | 36 | | | Mucinous AD | 7 | 3 | Papillary AD | 4 | 0 | Signet-ring cell carcinoma | 6 | 0 | Adenosquamous carcinoma | 0 | 1 |
| Tumor location | | | 3.334 | 0.343 | Upper 1/3 | 27 | 14 | | | Middle 1/3 | 5 | 5 | Lower 1/3 | 39 | 19 | Mix | 11 | 2 |
| Vascular invasion | | | 31.991 | <0.001 | (−) | 25 | 34 | | | (+) | 57 | 6 |
| Neural invasion | | | 13.922 | <0.001 | (−) | 32 | 30 | | | (+) | 50 | 10 |
| Lauren type | | | 1.600 | 0.206 | I (intestinal type) | 70 | 38 | | | D (diffuse type) | 5 | 2 | M (mixed type) | 7 | 0 |
| Tumor deposit | | | 3.940 | 0.047 | Yes | 18 | 3 | | | No | 64 | 37 |
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Abbreviations: AD-adenocarcinoma.
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