Research Article
ST8SIA6-AS1 Promotes the Epithelial-to-Mesenchymal Transition and Angiogenesis of Pituitary Adenoma
Figure 2
In pituitary adenoma, HOXA9 was directly targeted by miR-5195-3p. (a) Schematic diagram of the binding sites between miR-5195-3p and HOXA9. (b) The binding of miR-5195-3p to HOXA9 was verified by the dual luciferase reporter assay. (c) Verification of transfection efficiency of miR-5195-3p mimics. (d) Overexpression of miR-5195-3p inhibited the expression of HOXA9. (e) The co-expression of miR-5195-3p was negatively correlated with HOXA9. (f) Expression of miR-5195-3p in invasive pituitary adenoma tissues and noninvasive pituitary adenoma tissues was detected by qRT-PCR assay. ; n.s. means no statistical difference. , , and .
(a) |
(b) |
(c) |
(d) |
(e) |