Qici Sanling Decoction Suppresses Glutamine Consumption and Bladder Cancer Cell Growth through Inhibiting c-Myc Expression

Figure 2

QCSL increases cell apoptosis in T24 cells by repressing c-Myc expression. (a) mRNA and protein levels of c-Myc measured after transduction with vector and c-Myc overexpressing lentivirus. vs. vector. (b) Cell apoptosis assay performed after treatment with 0.5 mg/ml of QCSL and/or c-Myc overexpressing lentivirus. (c) Glutamine consumption detected after the same treatment as in b. (d) The mRNA and protein levels of GLS1, SLC1A5, and c-Myc. vs. vector; ^##, ^### vs. c-Myc + QCSL.

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