Long Intergenic Noncoding RNA 00641 Promotes Growth and Invasion of Colorectal Cancer through Regulating miR-450b-5p/GOLPH3 Axis

<div>Silencing LINC00641 suppressed the malignant behavior of CRC cells <i>in vitro</i>. (a) qRT-PCR determining the knockdown efficiency of shRNAs. (b) MTT assay was used to investigate the effect of LINC00641 on SW480 and HCT-116 proliferation. (c), (d) The effect of LINC00641 on cell cycle and apoptosis was determined by flow cytometry. (e), (f) Silencing LINC00641 inhibited the migration and invasion ability of SW480 and HCT-116 cells. Data are represented as mean ± SD of three biological replicates. 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Journal of Oncology

fig2

Figure 2

Figure 2: Long Intergenic Noncoding RNA 00641 Promotes Growth and Invasion of Colorectal Cancer through Regulating miR-450b-5p/GOLPH3 Axis 