Research Article
Long Noncoding RNA RMRP Contributes to Paclitaxel Sensitivity of Ovarian Cancer by Regulating miR-580-3p/MICU1 Signaling
Figure 2
RMRP contributes to the PTX resistance of ovarian cancer cells. (a, b) The cell viabilities of HeyA-8 and SKOV3 cells and PTX-resistant HeyA-8 (HeyA-8/PTX) and SKOV3 (SKOV3/PTX) cells were detected by MTT assays. (c) The expression of RMRP was measured in HeyA-8/PTX and SKOV3/PTX cells by qPCR. (d–g) The HeyA-8/PTX and SKOV3/PTX cells were treated with RMRP shRNA. (d, e) The cell viabilities were analyzed by MTT assays in HeyA-8/PTX and SKOV3/PTX cells. (f, g) The cell apoptosis was detected by flow cytometry in HeyA-8/PTX and SKOV3/PTX cells. shcontrol, control shRNA; shRMRP, RMRP shRNA. Mean ± SD, .
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