Research Article
Overexpression of LncRNA MNX1-AS1/PPFIA4 Activates AKT/HIF-1α Signal Pathway to Promote Stemness of Colorectal Adenocarcinoma Cells
Figure 5
Knockdown of PPFIA4 significantly inhibits the effect of MNX1-AS1 on stemness of COAD cells. (a) Expression of PPFIA4, compared to sh-Vector. (b, c) Spheroid formation of COAD stem cells, compared with MNX1-AS1 group, and compared with MNX1-AS1 + sh-PPFIA4 group. (d) Expression of tumor stemness markers, compared with control group, compared with MNX1-AS1 group, and compared with MNX1-AS1 + sh-PPFIA4 group.
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