Identification of a Signature for Predicting Prognosis and Immunotherapy Response in Patients with Glioma

Figure 3

(a) Protein-protein interaction network of DEGs in GSE was constructed using STRING software. (b) The top 100 genes network. The top 100 genes of the degree method were chosen using cytoHubba plugin. The more forward ranking is represented by red color. (c) Overlapping genes of meyellow + mebrown and top 100 hub genes. DEG: differentially expressed genes. (d) Six hub genes and their coexpression genes were analyzed using GeneMANIA. Nodes with white lines represent hub genes. Nodes without white lines represent coexpression genes. Hub genes are determined by the degree of connectivity between differentially expressed genes. The top six hub genes with the highest degree of connectivity were identified, including RAB3A, TYROBP, SYP, CAMK2A, VSIG4, and GABRA1.

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