Bee Venom Triggers Autophagy-Induced Apoptosis in Human Lung Cancer Cells via the mTOR Signaling Pathway

Figure 3

The mTOR pathway participated in bee venom-induced autophagy. (a and b) NCI-H460 cells were treated with bee venom (0.5 and 1 μg/ml) or 0.5 μM rapamycin for 24 h. The indicated protein levels were evaluated by immunoblotting. indicates a nonspecific band. (c) NCI-H460 cells were treated with 1 μg/ml bee venom for 24 h in the absence or presence of rapamycin (0.5 μM). LC3 levels were evaluated by immunoblotting.

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