The Safety and Feasibility of Laparoscopic Gastrectomy after Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer
Table 3
Surgical and pathological characteristics of population in this study.
Surgical and pathological features
LAG
OG
value
N = 77 (%)
N = 76 (%)
Laparoscopic exploration before NACT
0.980
Yes
71 (92.2)
69 (90.8)
No
6 (7.8)
7 (9.2)
Surgical radicalness
>0.999
R0
75 (97.4)
74 (97.4)
R1
2 (2.6)
2 (2.6)
Resection range
0.010
Distal
38 (49.4)
21 (27.6)
Total
39 (50.6)
55 (72.4)
Range of dissection
>0.999
D2
73 (94.8)
73 (96.1)
D2+
4 (5.2)
3 (3.9)
Operative duration
302.4 ± 49.9
296.6 ± 50.2
0.449
Intraoperative blood loss
91.1 ± 53.1
125.7 ± 116.9
0.024
Total no. of lymph nodes dissected
41.6 ± 12.4
40.0 ± 14.3
0.165
No. of lymph node metastasis
3.0 ± 4.8
4.6 ± 6.4
0.290
Differentiation
0.527
Well
0 (0)
2 (2.6)
Moderate
22 (28.6)
21 (27.6)
Poor
52 (65.7)
52 (68.4)
No evaluable (NE)
3 (3.9)
1 (1.3)
Signet-ring cell carcinoma
0.469
Yes
29 (37.7)
34 (44.7)
No
48 (62.3)
42 (55.3)
Lauren type
0.431
Intestinal
28 (36.4)
30 (39.5)
Mixed
17 (22.1)
23 (30.3)
Diffused
17 (22.1)
14 (18.4)
No evaluable (NE)#
15 (19.5)
9 (11.8)
Tumor regression grade
0.269
Grade 0
12 (15.6)
6 (7.9)
Grade 1
11 (14.3)
17 (22.4)
Grade 2
46 (59.7)
42 (55.3)
Grade 3
8 (10.4)
11 (14.5)
ypT stage
0.915
T0
8 (10.4)
5 (6.6)
T1a
8 (10.4)
5 (6.6)
T1b
8 (10.4)
7 (9.2)
T2
11 (14.3)
11 (14.5)
T3
25 (32.5)
29 (38.2)
T4a
16 (20.8)
17 (22.4)
T4b
1 (1.3)
2 (2.6)
ypN stage
0.531
N0
36 (46.8)
30 (39.5)
N1
15 (19.5)
13 (17.1)
N2
12 (15.6)
11 (14.5)
N3a
12 (15.6)
16 (21.1)
N3b
2 (2.6)
6 (7.9)
ypTNM stage
0.354
T0N0
7 (9.1)
5 (6.6)
T0N1
1 (1.3)
0 (0.0)
I
20 (26.0)
21 (27.6)
II
24 (31.2)
16 (21.1)
III
25 (32.5)
34 (44.7)
LAG, laparoscopy-assisted gastrectomy; OG, open gastrectomy; NACT, neoadjuvant chemotherapy. #NE indicates that the Lauren classification was not evaluable since the tumor regression after NACT; the yp stages were indicated by preoperative CT scan after neoadjuvant chemotherapy, and all staging was based on the eighth edition of the AJCC Cancer Staging Manual by the American Joint Committee on Cancer and International Union Against Cancer.
